http://localhost:80/xmlui/handle/123456789/194 2026-04-08T12:31:54Z http://localhost:80/xmlui/handle/123456789/207 Title: Review on Graphene Nanoparticle Composites Authors: Samaddar, Soma Abstract: In recent years, graphene has attracted attention. Grapheneis a thick planar sheet of sp 2 bonded carbon atoms. Its lattice is honey comb structure. Ciraphene is one of the most rising material due to its various fascinatingl properties. From recent study it is proved that graphene based composites with different nanoparticle show extensive application. In this review we focus on recent developement in the synthetic approach, properties and the facilities of use of graphene nanoparticle composites.The advantages of graphene-nanoparticle composites are specifically observed in catalytic reactions,electrochemical sensing, detection by surface enhanced Ratnan spectroscopy, purification of waterusing adsorbent and other applications are discussed here. 2021-01-01T00:00:00Z http://localhost:80/xmlui/handle/123456789/206 Title: Nanoparticles : Non-invasive Biomedical Imaging Agents Authors: Samaddar, Soma Abstract: The necessity for early detection of deadly diseases and to study the anatomical features of internal organs, there is an urge on the development of efficient and reliable method for biomedical imaging. This led to the emergence of nanoparticles as a versatile tool in cellular imaging. The main objective is to summarize the emerging research of nanoparticles for biomedical imaging with increased selectivity and reduced non-specific uptake by improved bioconjugation strategy. Quantum dots (fluorescent NPs), gold NPs and magnetic nanoparticles find several applications in in-vivo imaging techniques due to their exceptional properties. Toxicity of nanoparticles, however, remains a topic of concern which demands further investigation. Broader implication of this study includes improvement on the structural design of nanoparticles for in-vivo imaging and reduction of cytotoxicity. This review mainly emphasizes the properties and types of nanoparticles along with their applications in various imaging techniques. 2021-01-01T00:00:00Z http://localhost:80/xmlui/handle/123456789/205 Title: Enhancing Oncology with Nanorobotics Authors: Samaddar, Soma Abstract: Lung cancer was ranked 6 th among 'the top 10 global causes of death in 2019' by the World Health Organisation (WHO), with breast cancer and cervical cancer being the most common among Indian Women. The 2020 cancer death toll is devastating - approximately 10 million worldwide, with 8.5 hundred thousand in India. Common cancer therapies have a high failure rate because of various drawbacks - inefficient drug delivery, destruction of healthy cells around the tumor, and drug toxicity to name a few. The key attributes of efficient cancer management are - early-stage diagnosis and targeted therapy. Although nanomedicine has already been contributing to mitigate the drawbacks, advances in nanorobotics show that engineered nanorobots can be used to provide precision and expedition in early detection, and targeted drug delivery, ergo destruction of only cancer cells, leaving the normal cells alone. These computer-controlled nanomachines can be injected into symptomatic patients to perform diagnosis and therapy at a molecular level by sensing and destroying the cancer cells, and once their job is done, they would leave the body via excretory or respiratory systems. This would also minimize surgeon-patient contact. The application of nanorobotics in cancer theranostics, simultaneously performing diagnosis and therapy, holds a promising and revolutionized future of healthcare with an improved cancer survival rate. This review aims to outline the design, mechanism, applications in cancer diagnosis and therapy, and future outlook of nanorobots. 2021-01-01T00:00:00Z http://localhost:80/xmlui/handle/123456789/204 Title: Review On Arsenic Toxicity: Effect On Human Health And Biochemical Aspects Authors: Samaddar, Soma Abstract: Looking at the global scenario, it has been found that a huge percentage of population around the globe consider groundwater as their main source for drinking. But unfortunately, this main source is being heavily exposed to various heavy metals like mercury, cadmium, arsenic making it unfit for consumption, ultimately posing threat to human health out there. Although groundwater is considered as safe, but high concentrations of heavy metals like arsenic (As) (above the permissible limit) in ground water can pose risk to human health. Toxicity level of inorganic arsenic is more than the organic one. Arsenic contamination is having a worldwide effect. Arsenic is found to be carcinogenic in nature, gcnotoxic as well as cytotoxic. Prolonged exposure to arsenic causes various health hazards like arsenicosis, skin cancer, pigmentation, neurobehavioral effects, impaired intellect and various other chronic illness. Creating awareness and providing proper medical care still remains a big challenge. The biomarkers of arsenic exposure include nails, hair, urine and blood sample. This paper provides an overall overview of ground water arsenic contamination, its health hazards, its toxicity and metabolism in human body. The paper also reviews various analytical techniques that are being used to detect arsenic, the collective steps required to eradicate this global problem and provide high quality safe drinking water for the future generations to come. 2021-01-01T00:00:00Z